The use of 5 mg tadalafil once daily plus lidocaine anaesthetic spray in treatment of lifelong PE was more effective than tadalafil alone or lidocaine anaesthetic spray alone [Citation 120]. In a single- blind placebo-controlled clinical study, the combined use of on-demand dapoxetine
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domly assigned to the experimental group (n 50, tadalafil alone) or the active control group (n 48, tadalafil combined with lidocaine spray). Patients took tadalafil 30 min before sexual intercourse, while the combination therapy group also used lidocaine spray 5 min before intercourse.
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The use of 5 mg tadalafil once daily plus lidocaine anaesthetic spray in treatment of lifelong PE was more effective than tadalafil alone or lidocaine anaesthetic spray alone [Citation 120]. In a
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Conclusion: Tadalafil combined with lidocaine spray is superior to tadalafil alone in improving symptoms, prolonging IELT, and enhancing sexual satisfaction in patients with
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