Iron overload drugs

How is iron overload managed or treated? Iron overload due to haemochromatosis is often managed using venesection – a procedure where blood is

Iron overload is characterised by excessive iron deposition and consequent injury and dysfunction of target organs, especially the heart, liver, anterior pituitary, pancreas and joints. Iron overload disorders are common worldwide and occur in most major race/ethnicity groups. Physiological mechanisms to excrete iron are very limited. Thus, all patients with iron overload need safe and

-, Q ; link ; ABSTRACT: Iron overload has toxic effects on the body. Hepatotoxicity is a common finding in iron-overloaded patients, resulting

Iron overload occurs when there are high levels of iron the body. Symptoms include fatigue, weight loss, joint pain, and abdominal pain. Treatment for iron overload includes removing the iron from the body by using a chelating agent. A common drug class used to treat iron overload is the metal chelators drug class.

Deferiprone is the only orally active iron-chelating drug to be used therapeutically in conditions of transfusional iron overload. It is an orphan drug designed and developed primarily by academic initiatives for the treatment of iron overload in thalassaemia, which is endemic in the Mediterranean

In this opinion article, we focus on the treatment of typical HFE C282Y homozygotes with iron overload. Many of these management concepts also are applicable to the treatment of patients with other types of iron overload, although the severity of iron overload and response to phlebotomy vary depending on the genetic subtype of hemochromatosis or other iron overload disorder.

Deferoxamine is an iron-chelating agent, prescribed for acute iron poisoning and iron overload due to blood transfusion.

What is the current positioning of the drug? The benefits of iron chelation therapy in the treatment of patients with transfusional chronic iron overload are

iron overload. TREATMENT OF TRANSFUSION RELATED IRON OVERLOAD. All doses and drugs. Audiological Review when on Iron chelation. Desferrioxamine.