In addition, dabigatran, hirudins, and argatroban are direct inhibitors of thrombin. These drugs target thrombin within the common pathway and via FXa. A new
Argatroban and lepirudin are direct thrombin inhibitors. Argatroban reversibly binds to the catalytic site of thrombin.
Dabigatran is a Direct Thrombin Inhibitor. The mechanism of action of dabigatran is as a Thrombin Inhibitor. FDA Pharm Classes
Direct Factor Xa Inhibitors, Direct Thrombin Inhibitors, Disopyramide For brand name drugs under review and drug reviews completed on or before
Pradaxa is a direct thrombin inhibitor. Thrombin is an enzyme involved in the formation of blood clots. It works by blocking thrombin and
Argatroban is a direct, parenteral inhibitor of thrombin. Bivalirudin Bivalirudin is a modified form of hirudin with four glycine residues connecting two amino acids sequences important for binding to thrombin. It is a more reversible inhibitor of thrombin than is lepirudin, and is a direct, parenteral inhibitor of thrombin.
Direct Thrombin Inhibitors and Factor Xa Inhibitors
Direct oral anticoagulants; Direct oral thrombin inhibitors Dabigatran [3] Selective thrombin antagonist; For more information about other drugs from this class, see direct thrombin inhibitors under parenteral anticoagulation; Easily manageable (similar to heparins) when administered orally
Direct thrombin inhibitors: These drugs interfere with your body's use of thrombin, a key enzyme that helps clot your blood. Though it's
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