Notes Medications that prolong QT (e.g, quinidine, amiodarone) Nephrotoxic and ototoxic medications (e.g, furosemide, aminoglycosides, colistin, cisplatin)
Lipid intracytoplasmic inclusions, similar to amiodarone chloroquine Ototoxicity; Peripheral neuropathy; Hepatotoxicity; Retinopathy; Other: Diarrhea
acyclovir and tobramycin both increase nephrotoxicity and/or ototoxicity. Use Caution/Monitor. amikacin. amikacin and tobramycin both increase nephrotoxicity and/or ototoxicity. Modify Therapy/Monitor Closely. amiodarone. amiodarone will increase the level or effect of tobramycin by P-glycoprotein (MDR1) efflux transporter. Use Caution/Monitor.
Ototoxic Drug. search. Ototoxic Drug, Ototoxic Medication, Ototoxicity, Ototoxic Hearing Loss Ethacrynic Acid (Demadex); Furosemide (Lasix).
Possible Mechanisms of Amiodarone Neuro-/Ototoxicity There are no histopathologic reports of the effects of amiodarone on the vestibular nerve or the labyrinth. It is therefore not yet possible to pinpoint the exact location of the lesion in amiodarone-induced BVP along the vestibular system pathways.
by M Bisht 2024 Cited by 85Keywords Ototoxicity 4 Ototoxic drugs 4 Hearing loss. Adverse drug amiodarone, bretylium, disopyramide. Calcium channel blockers.
The authors reported their difficulty in adequately querying the databases. For example, querying one of the databases used in this analysis for the term ototoxicity did not encompass amiodarone; however, a query for the term bilateral vestibulopathy yielded only amiodarone as a result.
by LMP Faria 2024 Cited by 25amiodarone fentanyl; amiodarone simvastatin; gentamicin for nephrotoxicity and ototoxicity in patients, as well as changing
Ototoxicity [ ] Ototoxicity refers to hearing loss caused by a toxin. amiodarone; azimilide; bretylium; clofihium; tedisanil; ibutilide; sematilide
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