Is allopurinol safe for ckd patients

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Actual: Comparing Allopurinol vs Febuxostat in patients with CKD Nephpearls RheumJC
4.7 rating 2025-04-27
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by S Alobaidi 2024 Cited by 2prescription of allopurinol in CKD patients. Settings and Design: This was a retrospective study of adult patients prescribed allopur- inol with CKD (stages

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More CKD patients achieved a target uric acid level in studies where the allopurinol dose was titrated to effect as compared with those studies in which patients were given renally adjusted or untitrated allopurinol doses. Conclusions: Studies evaluating allopurinol use in patients with CKD have reported inconsistent findings relative to safety

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hypertension and chronic kidney disease (CKD) Stage 3, and Febuxostat has been found to be more effective in patients with. CKD than allopurinol given at

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by F Saliba 2024colchicine, may carry too much adverse risk for a particular patient. The Studies show allopurinol can safely reduce serum urate in CKD. However

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determine the rate of non-classical prescription of allopurinol in CKD patients. Settings and Design This was a retrospective study of adult patients prescribed allopurinol with CKD (stages 2 5) in Doctor Soliman Fakeeh Hospital (DSFH) Jeddah, Saudi Arabia, from to .

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This study suggests that allopurinol therapy has a mortality benefit in patients with gout and moderate-to-severe CKD.

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This study suggests that allopurinol therapy has a mortality benefit in patients with gout and moderate-to-severe CKD.

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There is limited evidence that allopurinol reduces CKD progression or cardiovascular events. It appears that AEs and in particular serious adverse events attributable to allopurinol are rare. However, the exact incidence of AEs in patients with CKD is unknown. Direct evidence for the impact of allopurinol on quality of life is lacking.

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Allopurinol: Currently recommended as first-line therapy even in patients with moderate-to-severe CKD, allopurinol should be initiated at a

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