Drugs that cause neutropenia

The most common drugs associated with severe neutropenia are antithyroid medications, ticlopidine, clozapine, sulfasalazine, trimethoprim-sulfamethoxazole, and dipyrone. 14 The mAb anti-CD20 (rituximab) also causes late-onset neutropenia. 15 If a potential causative agent is identifiable, drug-induced neutropenia is sometimes reversible at

Drug-induced neutropenia and agranulocytosis will be reviewed here. Others causes of acquired neutropenia, such as primary immune mechanisms, chemotherapy, and infections, as well as congenital neutropenia in children are discussed separately.

Drugs given to treat these infections may also cause neutropenia. (See Drug-induced neutropenia and agranulocytosis .) This review will discuss the neutropenias that can occur during bacterial, viral, parasitic, or rickettsial infections. Approaches to determining the cause of unexplained neutropenia in children and adults are presented

A G-CSF is a drug that doctors prescribe for treating neutropenia. Neutropenia is a condition that causes a person's white blood cell level to

produce leukopenia (and neutropenia) by damaging the bone marrow. Other drugs that cause neutropenia include pain relievers (analgesics), antihistamines

There are seven main types of neutropenia, each determined by the cause. These types are: Drug-induced neutropenia: Certain medications or treatments can reduce neutrophil counts. Autoimmune neutropenia: People with autoimmune neutropenia have antibodies that attack their neutrophils.

Others causes of acquired neutropenia, such as primary immune mechanisms, chemotherapy, and infections, as well as congenital neutropenia in children are discussed separately. (See Immune neutropenia and Infectious causes of neutropenia and Congenital neutropenia and Overview of neutropenic fever syndromes .)

FDA Drug Safety Communication: FDA modifies monitoring for neutropenia neutrophils in the blood, in some cases causing severe neutropenia.

causes of neutropenia (eg, bacterial, viral, fungal, and parasitic infections, nutritional deficiencies, copper deficiency, protein malnutrition, and immune reactions), drug therapy plays a significant role in causing neutropenia. Incidence Drug-induced neutropenia was first reported by Kracke in 2024, attributed to administration of an